With just over three weeks left until the presidential election, Hillary Clinton and Donald Trump are deadlocked in Ohio according to a new Quinnipiac University poll.

Clinton and Trump both stand at 45 percent. Trump held a 47-42 percent lead on October 3.

The big shift is among independent voters, who go from 52 - 33 percent for Trump October 3 to a virtual tie today, with 41 percent for Trump and 40 percent for Clinton. Republicans back Trump 89 - 6 percent, while Democrats go to Clinton 94 - 3 percent.

"Ohio has been Donald Trump's best of the major swing states, giving him a five-point lead earlier this month. But here, too, the controversies seem to be taking their toll on the Trump vote," says Peter A. Brown, assistant director of the Quinnipiac University Poll. "The race in the Buckeye state is a dead heat and the poll's internals show just how tight the race is there. Trump is leading by 14 points among men; Secretary Clinton up 12 points among women."

Brown believes Trump's best hope is a knockout win in the last debate Wednesday evening, his last shot at a national audience. "Once the Wednesday debate is over, the last three weeks of the campaign will be fought by competing turnout machines and TV commercials. Many observers believe Clinton has the superior ground game and money edge to dominate the airwaves."