Kicker Adam Vinatieri converted a 38-yard field goal to put the Colts up 17-13 with 3:19 remaining in the 3rd quarter.
Wide receiver Josh Gordon caught a 33-yard touchdown pass from Brandon Weeden on the opening drive of the second half.
Phil Dawson converted the extra point and the Browns trailed 14-13.
Gordon has caught a touchdown pass in three straight games for the Browns.
Colts quarterback Andrew Luck has two rushing touchdowns in the first half. The overall number-one pick in the NFL draft scored on a 3-yard run in the opening quarter that capped an 80-yard drive and a 5-yard run in the 2nd quarter.
Wide receiver Greg Little caught a 14-yard touchdown pass from Brandon Weeden to cap a 90-yard drive.
The Browns did not convert the extra point. The snap was good but Reggie Hodges could not hold on to the ball. Kicker Phil Dawson did not attempt the kick. The Colts lead 7-6 in the 2nd quarter.
The Browns have some momentum coming into today's game. Cleveland beat the Bengals last week 34-24.
Browns wide receiver Mohamed Massaquoi will not play today with a hamstring injury.
Be sure and watch Channel 3 news tonight at 6, 11 and on Browns Tonight for a complete recap of the Browns-Colts game.