CLEVELAND -- Temperatures in the 20s didn't stop hundreds of people from stripping down to their skivvies and taking a run through Cleveland's Tremont neighborhood on Saturday.

Around 800 men and women in their "bedroom best" dodged snowflakes for Cupid's Undie Run, a national fundraising event for the Children's Tumor Foundation.

Outrageous outfits were all part of the fun, but volunteers braved the cold for a serious mission. Participant Shannon Stipe explained that she was "trying to find a cure for me and my son. So he won't have to experience the pain that I'm going through, and the hundreds, and millions of other people out there who've had enough."

The goal of the one-mile run was to raise $50,000. But runners beat that by a mile -- raising $125,000 toward finding a cure for neurofibromatosis, a genetic disease that causes tumors and chronic pain.