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Ashley Judd said Wednesday she will not run for the U.S. Senate against Minority Leader Mitch McConnell of Kentucky.

The actress-activist, who had been considering running for the Democratic nomination, announced her decision on Twitter.

"After serious and thorough contemplation, I realize that my responsibilities and energy at this time need to be focused on my family," she said. "Regretfully, I am currently unable to consider a campaign for the Senate."

Democrats have made McConnell a top target for defeat in 2014.