Allergan will cut more than 1,000 jobs as part of its cost-reduction efforts, the company said in a filing Wednesday.

A photo taken on November 7, 2017 shows the Allergan company building in Pringy, eastern France.

The cuts will affect employees in commercial and other functions, Allergan said in a filing with the Securities and Exchange Commission. In addition to chopping existing jobs, the company will also eliminate 400 open positions.

Ireland-based Allergan, maker of Botox, expects the move to save it $300 million to $400 million this year. It anticipates the changes will cost $125 million, mainly due to severance expenses, the bulk of which is expected to be recorded in the fourth quarter.

The company said in November that it would undertake a cost-cutting and restructuring program, with CEO Brent Saunders telling analysts on an earnings call that Allergan was still in the planning phases but it saw "potential opportunities to become even more efficient."

Shares of Allergan have fallen more than 20% in the last 12 months. They were up 1.1% midday Wednesday.

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